Clinically Tested
Zero Stimulants
Vegan & GMP Certified
Designed by Microbiologists
Peer-Reviewed Research
GRAS-Status Strain
THE REAL CULPRIT
It's not the alcohol. It's what comes after.
Your liver turns ethanol into acetaldehyde — a compound that's up to 30× more toxic than alcohol itself. That's what's behind the headache, nausea, and brain fog the morning after.
Your body has enzymes (ALDH) that clear it, but they get overwhelmed fast. Counteract adds backup.
30×
More toxic than ethanol
ALDH2
The bottleneck enzyme
Group 1
IARC carcinogen class
~36%
People with a deficit
Deliver. Intercept. Clear.
Three steps. One capsule. The same pathway your body uses — just with serious reinforcements.
01
Deliver
Targeted release
Enteric coating gets the capsule past stomach acid, releasing ALDH enzymes in the upper intestine — exactly where alcohol is first absorbed.
→ Duodenum & jejunum
02
Intercept
Enzymatic shield
ALDH enzymes activate in the gut lumen and start intercepting acetaldehyde the moment it forms — before it enters your bloodstream.
→ Target: CH₃CHO
03
Clear
Metabolic conversion
Acetaldehyde → acetate (harmless) → CO₂ + water. The toxic load is cleared at the source. You wake up feeling like yourself.
→ Output: acetate → CO₂ + H₂O
THE SCIENCE
Engineered at the genetic level
Precision Gene Expression
We inserted a codon-optimized ALDH2 gene into a well-characterized Lactobacillus chassis under a constitutive promoter — ensuring reliable, continuous enzyme production without induction.
Gut-Targeted Delivery
Enteric microencapsulation protects viability through gastric transit, delivering >10⁹ CFU to the duodenum and jejunum where first-pass alcohol absorption peaks.
GRAS-Status Safety
Built on a Lactobacillus platform with decades of safe human use. Contains no antibiotic resistance markers. Biocontainment features prevent environmental persistence.
Clinically Validated
In a controlled crossover study (n=82), participants showed a 2.4× increase in acetaldehyde clearance rate and 71% reduction in next-morning symptom scores vs placebo.
Metabolic Pathway — With Counteract
THE PRODUCT
One capsule. Before your first drink.
No powders, no chasers, no complicated protocols. Just science that fits in your pocket.
1 capsule, 30 minutes before drinking
Enteric-coated for targeted release in the upper intestine. No need to redose throughout the night.
15 billion CFU per capsule
Engineered Lactobacillus expressing recombinant ALDH2. Shelf-stable at room temperature for 18 months.
Zero stimulants, fillers, or DHM
No caffeine, no herbal extracts, no band-aids. Counteract works through enzymatic action — the same pathway your body already uses.
10 capsules per bottle — $49
That's $4.90 per use. Less than a single drink at most bars. Ships free, subscription available at 20% off.
EARLY ACCESS
Don't take our word for it.
★ ★ ★ ★ ★
"Four glasses of wine at dinner. Woke up at 6am, ran 5K. That has literally never happened before."
Mei L. — Product Designer, 32
★ ★ ★ ★ ★
"As someone with Asian flush, this is the first thing that's actually addressed the root cause."
James K. — Physician, 41
★ ★ ★ ★ ★
"Bachelor party weekend. Three nights out, zero mornings wasted. My groomsmen are all subscribers now."
Daniel R. — Finance, 29
Got questions?
How is this different from other supplements?
+
Counteract is not a vitamin blend or herbal extract. It's an engineered probiotic that produces the ALDH2 enzyme — the same one your body uses to metabolize acetaldehyde, the toxic intermediate behind hangovers.
Is this a GMO?
+
Yes. Counteract uses a precision-edited Lactobacillus strain expressing recombinant human ALDH2. It is GRAS-status, biocontained, and carries no antibiotic resistance markers.
Will this stop me from getting drunk?
+
No. Counteract targets acetaldehyde — the toxic metabolite responsible for hangovers — not ethanol itself. You'll feel the same; you just won't pay for it the next morning.
What about Asian flush / ALDH2 deficiency?
+
Counteract was specifically designed with ALDH2-deficient individuals in mind. The supplemental enzyme provides backup capacity that the deficient native enzyme can't deliver.
When do I take it?
+
One capsule, 30 minutes before your first drink. The enteric coating ensures it activates in the upper intestine just as alcohol absorption begins.
Stop Recovering Start Counteracting
One capsule. One mechanism. Join 12,000+ on the waitlist. First shipments Q3 2026.
Pre-order Counteract — $49